I'm kind of a newb with VBox and trying to boost my VM performance any way possible to make it more useful, but my guess would be not to mess with much of the default settings in the Whonix workstation or gateway besides the RAM and CPU, right?
I found the host I/O caching to be of some help for performance but I wonder how big of a vulnerability the data exchange is. Is the data on the host an anonymity concern? Does it have any sensitive information? Looks like bidirectional copy/paste is enabled by default and I don't see how that would be much different...